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科学家发现角蛋白在早期胚胎发育中的不对称分配与细胞谱系特化
发布日期: 2021-09-04  访问量:

guanyufayuxingchengtaieryutaipandexibaopuxitehuadejutijizhi,kexuejiamentichuguojizhongbutongdelilun。“inside-outside”moxingrenweixibaopuxidetehuaguochengshiyouxibaofenliehousuochudenei-waiweizhichanshengdebutongweizhixinhaoyinfade。“yizhixingxueshuo”(heterogeneitiesmodel)renweizaisixibaoqijieduanduonengxingxibaoyuziyangcengxibaodexibaomingyunyijingchuxianbutong,zaizudanbaixiushi、zhuanluyinzidongtaibianhua、feibianmarnadedingweiyijijiyinbiaodadengfangfangmianmianchuxianqufen。xibaojixingmoxing(cellpolaritymodel)renweixibaobuduichengfenpeidexibaomingyunjuedingzufenqudonglebutongdexibaopuxitehuachansheng。danshi,zaiburudongwufayuguochengzhong,xibaojixingfenpeidezufenchengfenshifouyufeiburudongwupeitaizhongleisifahuizhebuduichengyichuanmingyunjuedingyinsudezuoyongyijitamenzaizaoqipeitaifayuyuxibaoyizhixingchanshengdeguanxishangbuqingchu。

2020nian8yue26ri,xinjiapoastarfenziyuxibaoshengwuxueyanjiusuonicolasplachtayanjiuzuzainaturezazhishangfabiaowenzhang“keratinsareasymmetricallyinheritedfatedeterminantsinthemammalianembryo”。gaiyanjiufaxianburudongwupeitaizhongyoujiaodanbai(keratins)zuoweibuduichengfenpeiyinzizaizaoqipeitaifayuguochengzhongduiyuziyangcengxibaotehuadeguanjiandiaokongzuoyong,weixibaojixingmoxingxueshuozengjialezhongyaokexueyiju,tongshijiaodanbaidebuduichengfenpeizairenleipeitaifayuguochengzhongyecunzai,zhengminglegaidiaokongjizhizaijinhuaguochengzhongdebaoshouxing。

benyanjiuzaitongqinaturezazhizhongbeizhongdiantuijian,duizheizhongzaitoufahezhijiazhongcunzaidewendingdanbaizhijuhewuzaiburudongwuzaoqifayudeguanjianjieduanweixibaotigongjixingdejiyidexinyingjizhijinxinglegaodupingjia。

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