guanyufayuxingchengtaieryutaipandexibaopuxitehuadejutijizhi，kexuejiamentichuguojizhongbutongdelilun。“inside-outside”moxingrenweixibaopuxidetehuaguochengshiyouxibaofenliehousuochudenei-waiweizhichanshengdebutongweizhixinhaoyinfade。“yizhixingxueshuo”（heterogeneitiesmodel）renweizaisixibaoqijieduanduonengxingxibaoyuziyangcengxibaodexibaomingyunyijingchuxianbutong，zaizudanbaixiushi、zhuanluyinzidongtaibianhua、feibianmarnadedingweiyijijiyinbiaodadengfangfangmianmianchuxianqufen。xibaojixingmoxing（cellpolaritymodel）renweixibaobuduichengfenpeidexibaomingyunjuedingzufenqudonglebutongdexibaopuxitehuachansheng。danshi，zaiburudongwufayuguochengzhong，xibaojixingfenpeidezufenchengfenshifouyufeiburudongwupeitaizhongleisifahuizhebuduichengyichuanmingyunjuedingyinsudezuoyongyijitamenzaizaoqipeitaifayuyuxibaoyizhixingchanshengdeguanxishangbuqingchu。
2020nian8yue26ri，xinjiapoastarfenziyuxibaoshengwuxueyanjiusuonicolasplachtayanjiuzuzainaturezazhishangfabiaowenzhang“keratinsareasymmetricallyinheritedfatedeterminantsinthemammalianembryo”。gaiyanjiufaxianburudongwupeitaizhongyoujiaodanbai（keratins）zuoweibuduichengfenpeiyinzizaizaoqipeitaifayuguochengzhongduiyuziyangcengxibaotehuadeguanjiandiaokongzuoyong，weixibaojixingmoxingxueshuozengjialezhongyaokexueyiju，tongshijiaodanbaidebuduichengfenpeizairenleipeitaifayuguochengzhongyecunzai，zhengminglegaidiaokongjizhizaijinhuaguochengzhongdebaoshouxing。
benyanjiuzaitongqinaturezazhizhongbeizhongdiantuijian，duizheizhongzaitoufahezhijiazhongcunzaidewendingdanbaizhijuhewuzaiburudongwuzaoqifayudeguanjianjieduanweixibaotigongjixingdejiyidexinyingjizhijinxinglegaodupingjia。